The rigidity of metallic multielectrode arrays often impedes long-term, stable neural signal recording due to mechanical mismatches, high interfacial impedance, and immune responses, compromising their biocompatibility. 

Our research will study the development of high-density, low-impedance, biocompatible soft neural probes. These probes are designed for capturing neural signals with enhanced spatiotemporal resolution and signal-to-noise ratios from the brain and nerves, while also reducing immune responses caused by mechanical mismatches and cytotoxicity at the electrode-tissue interface. This approach will facilitate stable, chronic recording and modulation of neural activities, significantly advancing our understanding of the brain and nervous system.

Neurological diseases significantly impact both individuals and society. Traditional electronic devices used for rehabilitating paralyzed limbs are often impractical for daily use due to their size, weight, and high power consumption. In contrast, our brain and nervous system process large amounts of information and respond appropriately using minimal power. 

Inspired by these efficiencies, we are developing soft electronic devices that mimic the functions of the brain and nervous system. Our focus on neuromorphic engineering, which mimics the information processing capabilities of the brain and the sensory/motor functions of the peripheral nervous system, has great potential not only in brain-inspired computing but also in biocompatible neuroprosthetics. Our approach will provide a low-power, soft neuromorphic rehabilitation device that is practical and efficient for daily use in patients with neural disorders.

Wearable devices capable of real-time monitoring of an individual's physical and mental health have proliferated. While band or watch-type wearables monitor various health information, their accuracy is limited due to unstable skin contact during daily activity. 

Our research focuses on developing soft wearable/implantable electronic devices that integrate seamlessly with the body and accommodate natural movements and deformations, enabling accurate health data collection. Using soft electronic materials and advanced manufacturing processes, we study new biomedical devices capable of measuring various digital biomarkers in brain engineering and cognitive neuroscience research.